Chronic respiratory diseases impose a substantial health burden globally with increasing prevalence and mortality rates, especially in affluent nations.Recent studies underscore the escalating contribution to premature morbidity and mortality, highlighting the critical need for effective interventions.Inflammatory lung diseases, such as asthma, chr
Prostate cancer (PCa) is the second most common cancer diagnosed in men.While radical prostatectomy and radiotherapy are often successful in treating localised disease, post-treatment recurrence is common.As the androgen receptor (AR) and androgen hormones play an essential role in prostate carcinogenesis and progression, androgen deprivation thera
In this study, the key findings of evaluating laser beam welding parameters on the multi-layered structure of 6061 aluminum alloys fabricating by accumulative roll bonding process are reported, considering fostering mechanical properties concerning the influence of filler metal and welding speed on the weld bead quality by taking into account reduc
The enhancer of zeste homologue 2 (EZH2), one of the polycomb group (PcG) proteins, is the catalytic subunit of Polycomb-repressive complex 2 (PRC2) and induces the trimethylation of the histone H3 lysine 27 (H3K27me3) promoting epigenetic gene silencing.EZH2 contains a SET domain promoting the methyltransferase activity while the three other prote